Tiana, dokter andrologi, menikah dengan Saka, pengusaha terkaya, demi menyelamatkan ibunya. Ia terseret konspirasi keluarga dan misteri kepribadian ganda Saka, yang muncul karena trauma adiknya tewas 17 tahun lalu. Bersama Tiana, Saka menghadapi pamannya Yuda, menyembuhkan trauma, menyatukan kepribadiannya, dan akhirnya menemukan cinta serta kedamaian dalam Keluarga Seta.
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